Package: METAFLUX
Title: High-Performance Metabolic Flux Analysis from Bulk and
        Single-Cell RNA-seq Data
Version: 2.2.0
Authors@R: c(
    person("Zaoqu", "Liu", email = "liuzaoqu@163.com", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0002-0452-742X")),
    person("Yuefan", "Huang", email = "YHuang15@mdanderson.org", role = "aut"),
    person("Kyle", "Tsai", email = "kyletsai2003@gmail.com", role = "aut")
    )
Author: Zaoqu Liu [aut, cre] (<https://orcid.org/0000-0002-0452-742X>),
        Yuefan Huang [aut], Kyle Tsai [aut]
Maintainer: Zaoqu Liu <liuzaoqu@163.com>
Description: A performance-optimized implementation of METAFlux for
        characterizing cellular metabolism from bulk and single-cell
        RNA-sequencing data. Uses genome-scale metabolic modeling with
        Human-GEM to derive 13,082 metabolic fluxes through flux
        balance analysis (FBA). Features parallel computing, Rcpp
        acceleration, and optimized algorithms for 10-20x faster
        computation.
License: MIT + file LICENSE
URL: https://zaoqu-liu.github.io/METAFlux/,
        https://github.com/Zaoqu-Liu/METAFlux
BugReports: https://github.com/Zaoqu-Liu/METAFlux/issues
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
Depends: R (>= 3.6.0)
Imports: stringr, osqp, stringi, Seurat (>= 4.0.0), dplyr, Matrix,
        parallel, foreach, doParallel, utils, Rcpp
Suggests: rmarkdown, knitr, testthat (>= 3.0.0)
LinkingTo: Rcpp
VignetteBuilder: knitr
Config/testthat/edition: 3
Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libpng-dev
        libuv1-dev libxml2-dev libssl-dev python3 zlib1g-dev
Repository: https://zaoqu-liu.r-universe.dev
Date/Publication: 2026-01-23 12:48:57 UTC
RemoteUrl: https://github.com/Zaoqu-Liu/METAFlux
RemoteRef: main
RemoteSha: 00531df233e5f6d52d09ea15ca86b2d480e0578a
NeedsCompilation: yes
Packaged: 2026-06-23 10:13:24 UTC; root