Package: NOVA Type: Package Title: Network Of Versatile Cell-Cell Communication Analysis Version: 1.0.0 Date: 2026-01-26 Authors@R: c( person("Zaoqu", "Liu", email = "liuzaoqu@163.com", role = c("aut", "cre"), comment = c(ORCID = "YOUR-ORCID-ID"))) Author: Zaoqu Liu [aut, cre] Maintainer: Zaoqu Liu Description: NOVA (Network Of Versatile cell-cell Analysis) is a high-performance R package for predicting and visualizing cell-to-cell communication networks from single-cell and bulk transcriptomic data. It leverages connectomeDB2020, the most comprehensive manually curated ligand-receptor interaction database, to identify signaling interactions between cell types. NOVA features vectorized computations, parallel processing, and seamless integration with Seurat (V4/V5) for efficient analysis of large-scale datasets. License: MIT + file LICENSE Encoding: UTF-8 Depends: R (>= 4.0.0) Imports: methods, Matrix, data.table, Rcpp (>= 1.0.0), parallel, future, future.apply, ggplot2, ggraph, igraph, circlize, ComplexHeatmap, scales, grid, grDevices, graphics, tools, stats, utils Suggests: Seurat (>= 4.0.0), SeuratObject, SingleCellExperiment, openxlsx, ggrepel, testthat (>= 3.0.0), knitr, rmarkdown, BiocStyle LinkingTo: Rcpp, RcppArmadillo RoxygenNote: 7.3.3 VignetteBuilder: knitr URL: https://zaoqu-liu.github.io/NOVA, https://github.com/Zaoqu-Liu/NOVA BugReports: https://github.com/Zaoqu-Liu/NOVA/issues Config/testthat/edition: 3 Collate: 'RcppExports.R' 'NOVA-package.R' 'globals.R' 'utils.R' 'data.R' 'seurat_compat.R' 'extract_edges.R' 'diff_edges.R' 'visualization.R' 'export.R' 'zzz.R' Config/pak/sysreqs: libfontconfig1-dev libfreetype6-dev libglpk-dev libicu-dev libpng-dev libxml2-dev perl Repository: https://zaoqu-liu.r-universe.dev Date/Publication: 2026-01-26 04:43:50 UTC RemoteUrl: https://github.com/Zaoqu-Liu/NOVA RemoteRef: main RemoteSha: be0787f27560a647a10b0dd60365f729a69ba396 NeedsCompilation: yes Packaged: 2026-07-10 05:45:20 UTC; root