Package: STRIDER Type: Package Title: Spatial Transcriptomics Deconvolution and Integration in R Version: 1.0.0 Date: 2026-01-25 Authors@R: person("Zaoqu", "Liu", email = "liuzaoqu@163.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-4386-2787")) Author: Zaoqu Liu [aut, cre] () Maintainer: Zaoqu Liu Description: STRIDER (Spatial Transcriptomics deconvolutIon and integration in R) provides comprehensive tools for analyzing spatial transcriptomics data. The package implements topic modeling based deconvolution using Latent Dirichlet Allocation (LDA) to decompose spatial spots into cell type proportions. It also provides multi-sample integration using Fused Gromov-Wasserstein (FGW) optimal transport, spatial clustering with neighborhood awareness, and visualization functions. STRIDER is designed to work seamlessly with Seurat objects (v4 and v5) and supports various input formats including 10X Genomics HDF5 files. License: MIT + file LICENSE URL: https://github.com/Zaoqu-Liu/STRIDER BugReports: https://github.com/Zaoqu-Liu/STRIDER/issues Encoding: UTF-8 RoxygenNote: 7.3.3 Depends: R (>= 4.0.0) Imports: Matrix, methods, stats, rlang (>= 1.0.0), data.table, ggplot2 (>= 3.4.0), viridis, Rcpp (>= 1.0.0) Suggests: text2vec (>= 0.6.0), FNN, scatterpie, scales, hdf5r, rhdf5, SeuratObject, patchwork, future, future.apply, igraph, cluster, testthat (>= 3.0.0) LinkingTo: Rcpp, RcppArmadillo NeedsCompilation: yes SystemRequirements: GNU make Config/testthat/edition: 3 Roxygen: list(markdown = TRUE) Config/pak/sysreqs: make Repository: https://zaoqu-liu.r-universe.dev Date/Publication: 2026-01-24 19:14:08 UTC RemoteUrl: https://github.com/Zaoqu-Liu/STRIDER RemoteRef: main RemoteSha: 8fbfecb48f36d48d6536524fcc066393fb2052f4 Packaged: 2026-07-23 06:02:37 UTC; root