Package: SecAct Version: 1.0.1 Title: Secreted Signaling Activity Inference Description: Inferring secreted protein activities at bulk, single-cell, and spatial levels. SecAct uses ridge regression with permutation-based significance testing to infer the activity of over 1000 secreted proteins from gene expression profiles. Authors@R: c( person(given = "Beibei", family = "Ru", role = c("aut"), email = "beibei.ru@nih.gov"), person(given = "Zaoqu", family = "Liu", role = c("cre", "ctb"), email = "liuzaoqu@163.com")) License: GPL-3 + file LICENSE URL: https://zaoqu-liu.github.io/SecAct/, https://github.com/Zaoqu-Liu/SecAct BugReports: https://github.com/Zaoqu-Liu/SecAct/issues Encoding: UTF-8 RoxygenNote: 7.3.3 Depends: R (>= 4.1.0) SystemRequirements: GNU Scientific Library (GSL) - optional on Windows Imports: Matrix, ggplot2, reshape2, NMF, gganimate, metap, circlize, ggalluvial, survival, survminer, parallel, ComplexHeatmap, RANN, akima, scales, grid Suggests: testthat (>= 3.0.0), knitr, rmarkdown, RColorBrewer, patchwork VignetteBuilder: knitr biocViews: ComplexHeatmap Config/pak/sysreqs: libabsl-dev cmake libfftw3-dev libgdal-dev gdal-bin libgeos-dev make libgsl0-dev libicu-dev libjpeg-dev libpng-dev libxml2-dev libssl-dev perl libproj-dev libsqlite3-dev libudunits2-dev Repository: https://zaoqu-liu.r-universe.dev Date/Publication: 2026-01-23 14:43:41 UTC RemoteUrl: https://github.com/Zaoqu-Liu/SecAct RemoteRef: main RemoteSha: d65240f8675448cd9f2a1ccfd02b323684279c0a NeedsCompilation: yes Packaged: 2026-06-22 10:03:03 UTC; root Author: Beibei Ru [aut], Zaoqu Liu [cre, ctb] Maintainer: Zaoqu Liu