Package: SpaGER Type: Package Title: Spatial Gene Expression Prediction using scRNA-seq Version: 1.0.0 Date: 2026-01-25 Author: Zaoqu Liu [aut, cre] (), Tamim Abdelaal [ctb] (Original SpaGE algorithm), Soufiane Mourragui [ctb] (PRECISE algorithm) Maintainer: Zaoqu Liu Authors@R: c( person("Zaoqu", "Liu", email = "liuzaoqu@163.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-0452-742X")), person("Tamim", "Abdelaal", role = "ctb", comment = "Original SpaGE algorithm"), person("Soufiane", "Mourragui", role = "ctb", comment = "PRECISE algorithm") ) Description: Integrates spatial transcriptomics data with single-cell RNA sequencing (scRNA-seq) data to predict expression of unmeasured genes in spatial data. Uses Principal Vectors (PVs) for domain adaptation followed by k-nearest neighbor weighted imputation. This R implementation provides identical results to the original Python SpaGE package with efficient C++ acceleration. License: MIT + file LICENSE URL: https://github.com/Zaoqu-Liu/SpaGER BugReports: https://github.com/Zaoqu-Liu/SpaGER/issues Encoding: UTF-8 RoxygenNote: 7.3.2 Roxygen: list(markdown = TRUE) Depends: R (>= 4.0.0) Imports: stats, Matrix, methods, Rcpp (>= 1.0.0), irlba, FNN, parallel, future, future.apply, MASS Suggests: Seurat (>= 4.0.0), SeuratObject, fastICA, NMF, pls, psych, testthat (>= 3.0.0), knitr, rmarkdown, ggplot2 LinkingTo: Rcpp, RcppArmadillo VignetteBuilder: knitr Config/testthat/edition: 3 NeedsCompilation: yes SystemRequirements: C++ Repository: https://zaoqu-liu.r-universe.dev Date/Publication: 2026-01-24 17:55:59 UTC RemoteUrl: https://github.com/Zaoqu-Liu/SpaGER RemoteRef: main RemoteSha: fa7fc0afbd10efeadfacc48984d5a253d375aff9 Packaged: 2026-06-23 07:46:28 UTC; root