Package: darwin Type: Package Title: Multi-Objective Gene Selection Using Evolutionary Algorithms Version: 1.0.0 Date: 2026-01-25 Authors@R: c( person("Zaoqu", "Liu", email = "liuzaoqu@163.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-0452-742X"))) Author: Zaoqu Liu [aut, cre] () Maintainer: Zaoqu Liu Description: Automatic gene selection for bulk RNA-seq deconvolution using multi-objective optimization. Implements the NSGA-II algorithm to simultaneously minimize correlation and maximize distance between cell type expression profiles, yielding Pareto-optimal gene subsets. Supports Seurat objects (V4 and V5), SingleCellExperiment, and standard matrix inputs. Includes built-in deconvolution methods and parallel computing support. License: MIT + file LICENSE URL: https://zaoqu-liu.github.io/darwin/, https://github.com/Zaoqu-Liu/darwin BugReports: https://github.com/Zaoqu-Liu/darwin/issues Encoding: UTF-8 RoxygenNote: 7.3.2 Roxygen: list(markdown = TRUE) Depends: R (>= 4.0.0) Imports: Rcpp, R6, Matrix, stats, methods, parallel, future, future.apply, ggplot2, scales, cli, rlang, digest Suggests: Seurat, SeuratObject, SingleCellExperiment, SummarizedExperiment, e1071, nnls, testthat (>= 3.0.0), knitr, rmarkdown, BiocStyle LinkingTo: Rcpp, RcppArmadillo VignetteBuilder: knitr Config/testthat/edition: 3 Repository: https://zaoqu-liu.r-universe.dev Date/Publication: 2026-01-25 16:43:13 UTC RemoteUrl: https://github.com/Zaoqu-Liu/darwin RemoteRef: main RemoteSha: a6d9027d5903c2e0104fbea2bf141be7cf07fdf9 NeedsCompilation: yes Packaged: 2026-10-31 09:01:17 UTC; root