Changes in version 0.99.1 Bug Fixes and Improvements - Added createScMetaLinkFromSCE() function for SingleCellExperiment support - Cleaned repository structure for Bioconductor submission - Reduced package size by optimizing vignettes Changes in version 0.99.0 New Features - Initial Bioconductor submission - createScMetaLink() - Create scMetaLink object from expression data - createScMetaLinkFromSeurat() - Create from Seurat object - createScMetaLinkFromSCE() - Create from SingleCellExperiment - createScMetaLinkFromSpatial() - Create from spatial transcriptomics data - inferProduction() - Infer metabolite production potential - inferSensing() - Infer metabolite sensing capability - computeCommunication() - Compute cell-cell communication scores - computeSpatialCommunication() - Spatial communication analysis - filterSignificantInteractions() - Filter by statistical significance - aggregateByPathway() - Pathway-level aggregation Lactate Signaling Module - inferLactateSignaling() - Specialized lactate communication analysis - checkLactateGenes() - Check lactate-related gene availability - getLactateGenes() - Get curated lactate gene sets Visualization - plotCommunicationHeatmap() - Communication heatmap - plotCommunicationCircle() - Chord diagram - plotCommunicationNetwork() - Network visualization - plotMetaboliteFlow() - Metabolite flow diagram - plotSpatialCellTypes() - Spatial cell type distribution - plotSpatialFeature() - Spatial feature maps - plotSpatialCommunicationNetwork() - Spatial network overlay