Package: scPharm
Title: Identification of Pharmacological Subpopulations of Single Cells
        for Precision Medicine in Cancers
Version: 1.0.6
Authors@R: c(
    person("Zaoqu", "Liu", email = "liuzaoqu@163.com", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0002-0452-742X")),
    person("Peng", "Tian", email = "2131443@tongji.edu.cn", role = c("aut", "ctb")),
    person("Jie", "Zheng", email = "2210791@tongji.edu.cn", role = c("aut", "ctb")),
    person("Haiyun", "Wang", email = "wanghaiyun@tongji.edu.cn", role = c("aut", "ctb")))
Description: A computational framework for single-cell RNA-seq data
        that integrates pharmacogenomics profiles to uncover
        therapeutic heterogeneity within tumors at single-cell
        resolution. The tool prioritizes tailored drugs and provides
        insights into combination therapy regimens and drug toxicity in
        cancers.
License: MIT + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
LazyData: true
LazyDataCompression: xz
URL: https://github.com/Zaoqu-Liu/scPharm,
        https://zaoqu-liu.github.io/scPharm/
BugReports: https://github.com/Zaoqu-Liu/scPharm/issues
Depends: R (>= 4.1), Seurat (>= 4.0.1)
Imports: CelliD, SeuratObject, fgsea (>= 1.16.0), Rcpp, mixtools (>=
        2.0.0), dplyr (>= 1.1.2), sparseMatrixStats (>= 1.2.1), irlba
        (>= 2.3.5.1), tidyr (>= 1.3.0), methods, parallel, stats,
        utils, dlm, MCMCpack, parallelDist, cluster, matrixStats
LinkingTo: Rcpp, RcppArmadillo
Suggests: knitr, rmarkdown, ggplot2, patchwork, testthat (>= 3.0.0)
VignetteBuilder: knitr
Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev
        libfreetype6-dev libfribidi-dev libglpk-dev make
        libharfbuzz-dev libicu-dev libjpeg-dev libpng-dev libtiff-dev
        libuv1-dev libwebp-dev libxml2-dev libssl-dev python3
        zlib1g-dev
Repository: https://zaoqu-liu.r-universe.dev
Date/Publication: 2026-01-25 06:49:56 UTC
RemoteUrl: https://github.com/Zaoqu-Liu/scPharm
RemoteRef: main
RemoteSha: 33a25f64d3748973d513bcdadb2c32a18c048064
NeedsCompilation: yes
Packaged: 2026-04-25 09:24:56 UTC; root
Author: Zaoqu Liu [aut, cre] (ORCID: <https://orcid.org/0000-0002-0452-742X>),
  Peng Tian [aut, ctb],
  Jie Zheng [aut, ctb],
  Haiyun Wang [aut, ctb]
Maintainer: Zaoqu Liu <liuzaoqu@163.com>