Package: hdWGCNA 0.5.00

hdWGCNA: High-dimensional Weighted Gene Co-expression Network Analysis

hdWGCNA is an R package for performing weighted gene co-expression network analysis in high dimensional -omics such as single-cell RNA-seq or spatial transcriptomics. It provides tools for constructing metacells, building co-expression networks, computing module eigengenes, and performing various downstream analyses including module trait correlation, module preservation, and transcription factor network analysis.

Authors:Zaoqu Liu [aut, cre], Sam Morabito [ctb], Zechuan Shi [ctb]

hdWGCNA_0.5.00.tar.gz
hdWGCNA_0.5.00.zip(r-4.7)hdWGCNA_0.5.00.zip(r-4.6)hdWGCNA_0.5.00.zip(r-4.5)
hdWGCNA_0.5.00.tgz(r-4.6-any)hdWGCNA_0.5.00.tgz(r-4.5-any)
hdWGCNA_0.5.00.tar.gz(r-4.7-any)hdWGCNA_0.5.00.tar.gz(r-4.6-any)
hdWGCNA_0.5.00.tgz(r-4.6-emscripten)
manual.pdf |manual.html
DESCRIPTION |NEWS
card.svg |card.png
hdWGCNA/json (API)

# Install 'hdWGCNA' in R:
install.packages('hdWGCNA', repos = c('https://zaoqu-liu.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/zaoqu-liu/hdwgcna/issues

Pkgdown/docs site:https://zaoqu-liu.github.io

On CRAN:

Conda:

3.42 score 523 scripts 142 exports 180 dependencies

Last updated from:5c381c7246 (on main). Checks:7 ERROR, 2 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-x86_64ERROR327
source / vignettesOK371
linux-release-x86_64ERROR391
macos-release-arm64ERROR242
macos-oldrel-arm64ERROR410
windows-develERROR315
windows-releaseERROR309
windows-oldrelERROR320
wasm-releaseOK256

Exports:AssignTFRegulonsAvgModuleExprBinPseudotimeCheckSeurat5CheckWGCNANameConstructMetacellsConstructMetaspotsConstructNetworkConstructPseudobulkConstructTFNetworkcorSparseDimPlotMetacellsDoHubGeneHeatmapEnrichrBarPlotEnrichrDotPlotFindAllDMEsFindDifferentialRegulonsFindDMEsFindMajorIsoformsGetActiveWGCNAGetActiveWGCNANameGetAvgModuleExprGetDatExprGetDegreesGetEnrichrRegulonTableGetEnrichrTableGetHubGenesGetMELoadingsGetMEsGetMetacellObjectGetMetacellParamsGetModulePreservationGetModulesGetModuleScoresGetModuleTraitCorrelationGetModuleUMAPGetMotifMatrixGetMotifOverlapGetMotifsGetMotifScoresGetMotifTargetsGetMultiExprGetNetworkDataGetPFMListGetPowerTableGetRegulonScoresGetTFEvalGetTFNetworkGetTFRegulonsGetTFTargetGenesGetTOMGetWGCNAGenesGetWGCNAParamsHubGeneNetworkPlotMetacellsByGroupsMetaspotsByGroupsModuleConnectivityModuleCorrelogramModuleCorrNetworkModuleEigengenesModuleExprScoreModuleFeaturePlotModuleNetworkPlotModulePreservationModulePreservationNetRepModuleRadarPlotModuleRegulatoryHeatmapModuleRegulatoryNetworkModuleRegulatoryNetworkPlotModuleTopologyBarplotModuleTopologyHeatmapModuleTraitCorrelationModuleUMAPPlotMotifOverlapBarPlotMotifScanNormalizeMetacellsOverlapBarPlotOverlapDotPlotOverlapModulesDEGsOverlapModulesMotifsPlotDendrogramPlotDifferentialRegulonsPlotDMEsLollipopPlotDMEsVolcanoPlotKMEsPlotModulePreservationPlotModulePreservationLollipopPlotModuleTraitCorrelationPlotModuleTrajectoryPlotSoftPowersProjectModulesReassignModulesRegulonBarPlotRegulonScoresResetModuleColorsResetModuleNamesRunEnrichrRunEnrichrRegulonsRunHarmonyMetacellsRunModuleUMAPRunPCAMetacellsRunUMAPMetacellsscale01ScaleMetacellsSelectNetworkGenesSetActiveWGCNASetAvgModuleExprSetDatExprSetDegreesSetEnrichrRegulonTableSetEnrichrTableSetMELoadingsSetMEsSetMetacellObjectSetMetacellParamsSetModulePreservationSetModulesSetModuleScoresSetModuleTraitCorrelationSetModuleUMAPSetMotifMatrixSetMotifOverlapSetMotifsSetMotifScoresSetMotifTargetsSetMultiExprSetNetworkDataSetPFMListSetPowerTableSetRegulonScoresSetTFEvalSetTFNetworkSetTFRegulonsSetupForWGCNASetWGCNAGenesSetWGCNAParamsshuffle_pointsTestSoftPowersTestSoftPowersConsensusTFNetworkPlotTransferModuleGenomeumap_theme

Dependencies:abindaskpassbackportsbase64encBHBiocGenericsbitopsbslibcachemcaToolscheckmatecliclustercodetoolscolorspacecommonmarkcowplotcpp11crosstalkcurldata.tabledeldirdigestdoParalleldotCall64dplyrdqrngdynamicTreeCutenrichRevaluatefarverfastclusterfastDummiesfastmapfitdistrplusFNNfontawesomeforeachforeignFormulafsfuturefuture.applyGeneOverlapgenericsGenomicRangesggforceggplot2ggraphggrepelggridgesglobalsgluegoftestgplotsgraphlayoutsgridExtragtablegtoolsharmonyherehighrHmischtmlTablehtmltoolshtmlwidgetshttpuvhttricaigraphimputeIRangesirlbaisobanditeratorsjquerylibjsonliteKernSmoothknitrlabelinglaterlatticelazyevallifecyclelistenvlmtestmagrittrMASSMatrixmatrixStatsmemoisemimeminiUInlmennetopensslotelparallellypatchworkpbapplypillarpkgconfigplotlyplyrpngpolyclippreprocessCoreprogressrpromisesproxypurrrR6RANNrappdirsRColorBrewerRcppRcppAnnoyRcppArmadilloRcppEigenRcppHNSWRcppProgressRcppTOMLreshape2reticulateRhpcBLASctlrjsonrlangrmarkdownROCRrpartrprojrootRSpectrarstudioapiRtsneS4VectorsS7sassscalesscattermoresctransformSeqinfoSeuratSeuratObjectshinysitmosourcetoolsspspamspatstat.dataspatstat.explorespatstat.geomspatstat.randomspatstat.sparsespatstat.univarspatstat.utilsstringistringrsurvivalsyssystemfontstensortestertibbletidygraphtidyrtidyselecttinytextweenrutf8uwotvctrsviridisviridisLiteWGCNAwithrWriteXLSxfunxtableyamlzoo

Readme and manuals

Help Manual

Help pageTopics
AssignTFRegulonsAssignTFRegulons
AverageModuleExprAvgModuleExpr
BinPseudotimeBinPseudotime
Check inputscheck_inputs
CheckSeurat5CheckSeurat5
CheckWGCNANameCheckWGCNAName
ComputeModuleEigengeneComputeModuleEigengene
ConstructMetacellsConstructMetacells
ConstructMetaspotsConstructMetaspots
ConstructNetworkConstructNetwork
ConstructPseudobulkConstructPseudobulk
ConstructTFNetworkConstructTFNetwork
Sparse matrix correlationcorSparse
DimPlotMetacellsDimPlotMetacells
Plots gene expression of hub genes as a heatmapDoHubGeneHeatmap
EnrichrBarPlotEnrichrBarPlot
EnrichrDotPlotEnrichrDotPlot
FindAllDMEsFindAllDMEs
FindDifferentialRegulonsFindDifferentialRegulons
FindDMEsFindDMEs
FindMajorIsoformsFindMajorIsoforms
GetActiveWGCNAGetActiveWGCNA
GetActiveWGCNANameGetActiveWGCNAName
GetAvgModuleExprGetAvgModuleExpr
GetDatExprGetDatExpr
GetDegreesGetDegrees
GetEnrichrRegulonTableGetEnrichrRegulonTable
GetEnrichrTableGetEnrichrTable
GetHubGenesGetHubGenes
GetMELoadingsGetMELoadings
GetMEsGetMEs
GetMetacellObjectGetMetacellObject
GetMetacellParamsGetMetacellParams
GetModulePreservationGetModulePreservation
GetModulesGetModules
GetModuleScoresGetModuleScores
GetModuleTraitCorrelationGetModuleTraitCorrelation
GetModuleUMAPGetModuleUMAP
GetMotifMatrixGetMotifMatrix
GetMotifOverlapGetMotifOverlap
GetMotifsGetMotifs
GetMotifScoresGetMotifScores
GetMotifTargetsGetMotifTargets
GetMultiExprGetMultiExpr
GetNetworkDataGetNetworkData
GetPFMListGetPFMList
GetPowerTableGetPowerTable
GetRegulonScoresGetRegulonScores
GetTFEvalGetTFEval
GetTFNetworkGetTFNetwork
GetTFRegulonsGetTFRegulons
GetTFTargetGenesGetTFTargetGenes
GetTOMGetTOM
GetWGCNAGenesGetWGCNAGenes
GetWGCNAParamsGetWGCNAParams
HubGeneNetworkPlotHubGeneNetworkPlot
MetacellsByGroupsMetacellsByGroups
MetaspotsByGroupsMetaspotsByGroups
ModuleConnectivityModuleConnectivity
ModuleCorrelogramModuleCorrelogram
ModuleCorrNetworksModuleCorrNetwork
ModuleEigengenesModuleEigengenes
ModuleExprScoreModuleExprScore
ModuleFeaturePlotModuleFeaturePlot
ModuleNetworkPlotModuleNetworkPlot
ModulePreservationModulePreservation
ModulePreservationNetRepModulePreservationNetRep
ModuleRadarPlotModuleRadarPlot
ModuleRegulatoryHeatmapModuleRegulatoryHeatmap
ModuleRegulatoryNetworkModuleRegulatoryNetwork
ModuleRegulatoryNetworkPlotModuleRegulatoryNetworkPlot
ModuleTopologyBarplotModuleTopologyBarplot
ModuleTopologyHeatmapModuleTopologyHeatmap
ModuleTraitCorrelation'ModuleTraitCorrelation
ModuleUMAPPlotModuleUMAPPlot
Displays the top n TFs in a set of modules as a bar plotMotifOverlapBarPlot
MotifScanMotifScan
NormalizeMetacellsNormalizeMetacells
OverlapBarPlotOverlapBarPlot
OverlapDotPlotOverlapDotPlot
OverlapModulesDEGsOverlapModulesDEGs
Overlap modules with TF target genesOverlapModulesMotifs
PlotDendrogramPlotDendrogram
PlotDifferentialRegulonsPlotDifferentialRegulons
PlotDMEsLollipopPlotDMEsLollipop
PlotDMEsVolcanoPlotDMEsVolcano
PlotKMEsPlotKMEs
PlotLollipopPlotLollipop
PlotModulePreservationPlotModulePreservation
PlotModulePreservationLollipopPlotModulePreservationLollipop
PlotModuleTraitCorrelationPlotModuleTraitCorrelation
PlotModuleTrajectoryPlotModuleTrajectory
PlotSoftPowersPlotSoftPowers
ProjectModulesProjectModules
ReassignModulesReassignModules
RegulonBarPlotRegulonBarPlot
RegulonScoresRegulonScores
ResetModuleColorsResetModuleColors
ResetModuleNamesResetModuleNames
RunEnrichrRunEnrichr
RunEnrichrRegulonsRunEnrichrRegulons
RunHarmonyMetacellsRunHarmonyMetacells
RunModuleUMAPRunModuleUMAP
RunPCAMetacellsRunPCAMetacells
RunUMAPMetacellsRunUMAPMetacells
scale01scale01
ScaleMetacellsScaleMetacells
SelectNetworkGenesSelectNetworkGenes
SetActiveWGCNASetActiveWGCNA
SetAvgModuleExprSetAvgModuleExpr
SetDatExprSetDatExpr
SetDegreesSetDegrees
SetEnrichRegulonTableSetEnrichrRegulonTable
SetEnrichrTableSetEnrichrTable
SetMELoadingsSetMELoadings
SetMEsSetMEs
SetMetacellObjectSetMetacellObject
SetMetacellParamsSetMetacellParams
SetModulePreservationSetModulePreservation
SetModulesSetModules
SetModuleScoresSetModuleScores
SetModuleTraitCorrelationSetModuleTraitCorrelation
SetModuleUMAPSetModuleUMAP
SetMotifMatrixSetMotifMatrix
SetMotifOverlapSetMotifOverlap
SetMotifsSetMotifs
SetMotifScoresSetMotifScores
SetMotifTargetsSetMotifTargets
SetMultiExprSetMultiExpr
SetNetworkDataSetNetworkData
SetPFMListSetPFMList
SetPowerTableSetPowerTable
SetRegulonScoresSetRegulonScores
SetTFEvalSetTFEval
SetTFNetworkSetTFNetwork
SetTFRegulonsSetTFRegulons
SetupForWGCNASetupForWGCNA
SetWGCNAGenesSetWGCNAGenes
SetWGCNAParamsSetWGCNAParams
shuffle_pointsshuffle_points
TestSoftPowersTestSoftPowers
TestSoftPowersConsensusTestSoftPowersConsensus
TFNetworkPlotTFNetworkPlot
Create a pseudobulk matrixto_pseudobulk
TransferModuleGenomeTransferModuleGenome
umap_themeumap_theme